Perilla frutescens Extracts Enhance DNA Repair Response in UVB Damaged HaCaT Cells
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چکیده
منابع مشابه
NAD(+)-dependent repair of damaged DNA by human cell extracts.
Rejoining of DNA single-strand breaks generated by treatment of plasmids with gamma-rays, neocarzinostatin, or bleomycin was catalyzed inefficiently by human cell extracts. The reaction was strongly promoted by the addition of NAD+, which was employed for rapid and transient synthesis of poly(ADP-ribose). The DNA rejoining reaction was accompanied by DNA repair replication, apparently due to re...
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UVB radiation causes about 90% of non-melanoma skin cancers by damaging DNA either directly or indirectly by increasing levels of reactive oxygen species (ROS). Skin, chronically exposed to both endogenous and environmental pro-oxidant agents, contains a well-organised system of chemical and enzymatic antioxidants. However, increased or prolonged free radical action can overwhelm ROS defence me...
متن کاملPhytochemical study of polyphenols in Perilla Frutescens as an antioxidant
Perilla frutescens is an annual herb of the mint family native to East Asia. Polyphenols present in perilla have various structural varieties with large diversity of biological activities. It is direct influence the quality of perilla plant and their potential functions. Some of these products have been studied and proven to be effective source of phenolic antioxidants. The aqueous extract cont...
متن کاملSuppressive effects of Perilla frutescens on mesangioproliferative glomerulonephritis in rats.
Leaves of Perilla frutescens var. crispa DECNE. (perilla, Labiatae) are used as a garnishing vegetable in East Asian countries as well as an herbal medicine prescribed in Kampo medicines such as Saiboku-to. A previous in vitro study revealed that a decoction of perilla leaves inhibits the proliferation of murine-cultured mesangial cells. In the present study, we evaluated the in vivo anti-proli...
متن کاملPhytochemical study of polyphenols in Perilla Frutescens as an antioxidant
Perilla frutescens is an annual herb of the mint family native to East Asia. Polyphenols present in perilla have various structural varieties with large diversity of biological activities. It is direct influence the quality of perilla plant and their potential functions. Some of these products have been studied and proven to be effective source of phenolic antioxidants. The aqueous extract cont...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2021
ISSN: 2072-6643
DOI: 10.3390/nu13041263